Showing posts with label risks. Show all posts
Showing posts with label risks. Show all posts

Monday, December 17, 2012

Study links heart medication digoxin to deaths | Essentials

Posted by

Study links heart medication digoxin to deaths

Trick photo, decapitated man with bloody knife, holding his head
Trick photo, decapitated man with bloody knife, holding his head by George Eastman House
License (according to Flickr): No known copyright restrictions
Excerpt:

The study, which was published online in the European Heart Journal on Nov. 27, 2012, showed that patients who took digoxin who had atrial fibrillation (AF) -- a condition where the heart's upper chambers flutter erratically -- died in significant numbers while on the medication. Digoxin is made from an extract from the foxglove plant used on patients who have AF and heart failure. Theoretically, it makes the heart beat stronger and more regularly. It is notoriously hard to use because there is a narrow dose range between where it is helpful and when it can cause harm. High doses have been seen to increase death in patients. For the study, researchers looked at data from 4,060 AF patients who took digoxin before or during the 3. 5 year study.

People:

Dr. Ali Ahmed

Overall Sentiment: -0.282751

Relevance: 0.158512

SentimentQuote
0He said other "confounders" ...
-0.0931523"This should be taken with extreme caution, because of the potential for confounding and bias from a variety of sources," Ahmed, who wasn't involved in the new research, said. ...
Sentiment Stats:
  • Number of Quotes: 2
  • Aggregate Sentiment: -0.0931523
  • Mean: -0.04657615
  • Standard Deviation: 1.7320508075689

Claude Elayi

Overall Sentiment: -0.284806

Relevance: 0.14906

SentimentQuote
-0.0686159"These results mean that among AF patients taking digoxin compared to those not on digoxin in the AFFIRM trial, within five years one additional patient out of six will die from any cause, one additional patient out of eight will die from cardiovascular causes, and one additional patient out of 16 will die from arrhythmias," Samy Claude Elayi, associate professor of medicine at the Gill Heart Institute, University of Kentucky, in Lexington, Ky., said
-0.0362309"But in patients that have no heart failure and (have) atrial fibrillation, I think there is no reason to use this drug as a first line," Elayi said. ...
Sentiment Stats:
  • Number of Quotes: 2
  • Aggregate Sentiment: -0.1048468
  • Mean: -0.0524234
  • Standard Deviation: 0

Natasha Stewart

Overall Sentiment: 0.0544591

Relevance: 0.122953

Key:

  • Aggregate Sentiment is meant to be an indicator of an individual's overall sentiment.
  • The Mean is meant to be an indicator of an individual's average comment sentiment.
  • The Standard Deviation, when there are enough quotes, will indicate an individual's consistency of sentiment (i.e. a Standard Deviation of 0 would mean they were very consistent in their sentiment and 1 would mean they were very inconsistent).

Note that quote stats are likely to be meaningless beyond the aggregate score due to the tiny sample size. However, they are always provided just in case you find something useful there.

Additional Info:

Drug: digoxin

Overall Sentiment: -0.0394347

Relevance: 0.885512

URL Header Details
at
Labels: , , , ,
No comments:

Saturday, December 1, 2012

Study of antidepressants in pregnant women finds more risks than benefits | Redux

Posted by

Study of antidepressants in pregnant women finds more risks than benefits

Excerpt:

People:

SSRIs

Overall Sentiment: -0.142365

Relevance: 0.598245

Dr. Adam Urato

Overall Sentiment: 0

Relevance: 0.486234

SentimentQuote
0.180184Urato said, "This is a significant finding because we know that babies born before 37 weeks are at risk for many short and long-term health problems."
Sentiment Stats:
  • Number of Quotes: 1
  • Aggregate Sentiment: 0.180184
  • Mean: 0.180184
  • Standard Deviation: 1.4142135623731

Gregory Moore

Overall Sentiment: 0.500123

Relevance: 0.275858

Dr. Alice Domar

Overall Sentiment: 0.0424665

Relevance: 0.273206

SentimentQuote
0.0672362"There is enough evidence to strongly recommend that great caution be exercised before prescribing SSRI antidepressants to women who are pregnant or who are attempting to get pregnant, whether or not they are undergoing infertility treatment," study co-author Dr. Alice Domar, an OB/GYN at Beth Israel Deaconess Medical Center, said ...
0"There is enough evidence to strongly recommend that great caution be exercised before prescribing SSRI antidepressants to women who are pregnant or who are attempting to get pregnant, whether or not they are undergoing infertility treatment," study co-author Dr. Alice Domar, an OB/GYN at Beth Israel Deaconess Medical Center, said in the press release. "We want to stress that depressive symptoms should be taken seriously and should not go untreated prior to or during pregnancy, but there are other options out there that may be as effective, or more effective than SSRIs without all the attendant risks."
Sentiment Stats:
  • Number of Quotes: 2
  • Aggregate Sentiment: 0.0672362
  • Mean: 0.0336181
  • Standard Deviation: 1.7320508075689

Kimberly Yonkers

Overall Sentiment: 0

Relevance: 0.266811

Key:

  • Aggregate Sentiment is meant to be an indicator of an individual's overall sentiment.
  • The Mean is meant to be an indicator of an individual's average comment sentiment.
  • The Standard Deviation, when there are enough quotes, will indicate an individual's consistency of sentiment (i.e. a Standard Deviation of 0 would mean they were very consistent in their sentiment and 1 would mean they were very inconsistent).

Note that quote stats are likely to be meaningless beyond the aggregate score due to the tiny sample size. However, they are always provided just in case you find something useful there.

Additional Info:

Facility: Tufts Medical Center

Overall Sentiment: 0

Relevance: 0.339091

Facility: Beth Israel Deaconess Medical Center

Overall Sentiment: 0.0179959

Relevance: 0.322218

Country: U.S.

Overall Sentiment: 0

Relevance: 0.328645

Disambiguation: Location | Region | AdministrativeDivision | GovernmentalJurisdiction | FilmEditorReferences:

HealthCondition: postpartum depression

Overall Sentiment: -0.254507

Relevance: 0.805865

HealthCondition: miscarriage

Overall Sentiment: -0.142271

Relevance: 0.441065

Disambiguation: DiseaseOrMedicalCondition | CauseOfDeath | DiseaseReferences:

HealthCondition: depression

Overall Sentiment: 0.0187533

Relevance: 0.424333

Disambiguation: DiseaseOrMedicalCondition | CauseOfDeath | RiskFactor | DiseaseReferences:

HealthCondition: stroke

Overall Sentiment: 0.0320315

Relevance: 0.330633

Disambiguation: DiseaseOrMedicalCondition | CauseOfDeath | DiseaseCause | RiskFactor | Symptom | DiseaseReferences:

HealthCondition: seizures

Overall Sentiment: -0.567559

Relevance: 0.313732

Disambiguation: DiseaseOrMedicalCondition | CauseOfDeath | Symptom | DiseaseReferences:

HealthCondition: autism

Overall Sentiment: -0.212453

Relevance: 0.307169

Disambiguation: DiseaseOrMedicalCondition | Disease | OrganizationSectorReferences:

FieldTerminology: brain chemical serotonin

Overall Sentiment: -0.21357

Relevance: 0.318499

Organization: MetroWest Medical Center

Overall Sentiment: 0

Relevance: 0.342024

Organization: FDA

Overall Sentiment: -0.0745332

Relevance: 0.304198

Organization: American College of Obstetricians and Gynecologists' committee on ethics

Overall Sentiment: 0.223987

Relevance: 0.302303

Meta Info
at
Labels: , , , ,
No comments:
Subscribe to: Posts (Atom)